Analysis and confirmation of recombinant cell lines is very important. In contrast to the genes copy number, the chromosomal integration of a transgene (an exogenous gene) appears to be more considered. Due to the random nature of an integration event, several sites may be in capable of supporting the transcription of the transgene or the expression level is greatly influenced by the effect of the genetic environment at the gene locus (position effects).

G-banding is a technique used in cytogenetics to produce a visible karyotype by staining condensed chromosomes. It is useful for the identification of structural abnormalities through the photographic representation of the entire chromosome complement. Creative Bioarray has performed many karyotyping (banded chromosome analysis) services for cell line authentication and some specific research. In providing karyotyping information, we can promote the advancement of biology projects.

Creative Bioarray now offers a full line of circulating tumor cell Fluorescence in situ Hybridization (FISH) services, from enrichment of CTCs, standardized testing of validated assays and custom development of new assays.

Fluorescence in situ hybridization (FISH), developed in 1980s, is a cytogenetic technique using fluorescent probes to bind the chromosome with a high degree of complementarity. It is a powerful and easy method to detect RNA or DNA sequences in cells, tissues and tumors. This technique is useful for identifying chromosomal abnormalities, gene mapping, characterizing somatic cell hybrids, checking amplified genes and studying the mechanism of rearrangements. RNA FISH is used to measure and localize mRNAs and other transcripts within tissue sections or whole mounts.

With our experienced and professional scientists, Creative Bioarray offers the complete customized In Site Hybridization (ISH) service. They work closely with you on every step including probe design, tissue procurement and gene expression studies. We offer the strategy and experimental design that best fit your needs and herein to accelerate the speed to achieve your research goals. We also provide custom service which will dramatically reduce your operating costs by eliminating the complicated time-consuming processes of ISH away from your laboratory.

IHC is also a common method in basic research of disease to help understanding the distribution and localization of biomarkers and differentially expression of proteins in different parts of tissue. Creative Bioarray offers a comprehensive IHC service from project design, marker selection to image completion and data analysis. We are dedicated to satisfied every customer and assist them to achieve their specific research goals.

IHC, by exploiting the principle of antibodies binding specifically to antigens in biological tissues, is a routine method to detect antigens in cells of a tissue section. It is widely used in the diagnosis of diseases including cancer, neurological disease, digestive disease, etc. Specific molecular markers have been found and verified to be characteristic of particular cellular events in disease such as proliferation, apoptosis and inflammation. Thus it could be used in detection of such changes involved in disease.

Histology, the study of the microscopic anatomy of cells and tissues of plants and animals, commonly performed by examining cells and tissues under the microscope. It is frequently used in clinical research and basic research. Moreover, it is also an important tool in study of pathology. By using the specific antibody to bind the antigens, expression of antigens could be detected for diagnosis of disease, investigation of pathology, and localization of proteins.

Oncology is a branch of medicine that deals with the prevention, diagnosis and treatment of cancer. Research contains mechanism study (including molecule mechanism), pathological research, surgical method, medical treatment therapy (chemotherapy, radiotherapy), management for an individual patient, new drug development, etc. Obviously, oncology is often managed through discussion on multi-disciplinary.

Creative Bioarray is a leading company specialized in cell biology. Stem cells and regenerative medicine is a fast emerging field with rapid strides of progress and focus on human health. We have intelligent experts and perfect platform to ensure our performance in stem cell research. And we get high praise from our customers in quality and delivery time.