Creative Bioarray has developed human highly immortalized differentiated cell lines from various human tissues that show stable growth characteristics and phenotypes and have a high potential for production of complex biopharmaceuticals such as recombinant proteins, vaccines or extracellular vesicles.

Creative Bioarray STR profiling is critical for verifying the identity of human cell lines, ensuring the uniqueness of the cell line and detecting laboratory errors such as misidentification and cross-contamination of lines. The sensitivity and high power of discrimination makes our STR analysis an ideal choice for the various types of cell authentication.

Ionotropic glutamate receptors are ligand-gated ion channels which are activated by the neurotransmitter glutamate. Ionotropic glutamate receptors can be divided into 4 subgroups based on their pharmacology and sequence similarity.

Nicotinic acetylcholine receptors (nAChRs) are found in the central and peripheral nervous system, muscle, and many other tissues of many organisms which respond to the neurotransmitter acetylcholine. These receptors belong to a superfamily of ligand-gated ion channels and are known to play key roles in synaptic transmission throughout the central nervous system. Many subtypes of nAChR are known to exist, composed of different combinations of subunits which in combination with their broad distribution throughout the central and peripheral nervous systems, enable them to play multiple, varied roles.

P2X receptors are present in multiple organisms including humans, mouse, rat, rabbit, chicken, zebrafish, bullfrog, fluke, and amoeba.

Transient receptor potential channels (TRP) are non-selective calcium permeant cation channel located mostly on the plasma membrane of numerous animal cell types. They are involved in osmotic sensitivity and mechano-sensitivity. The exposure to hypotonicity within the physiological range induces some TRP channels activation exhibiting an outward rectification.

Voltage-gated chloride channels display a variety of important physiological and cellular roles that include regulation of pH, volume homeostasis, organic solute transport, cell migration, cell proliferation and differentiation. Based on sequence homology the chloride channels can be subdivided into a number of groups.

Voltage-gated potassium channel plays an important role in the rapid repolarization of fast-firing brain neurons. The channel opens in response to the voltage difference across the membrane, forming a potassium-selective channel through which potassium ions pass in accordance with their electrochemical gradient. The voltage-gated potassium channels are responsible for firing sustained trains of very brief action potentials at high frequency in pallidal neurons.

Calcium channel have been well recognized as therapeutic targets for treating a number of diseases. However, the calcium channel class is considered to be underexploited due to the lack of reliable functional cell-based assays for high-throughput screening.

Sodium channels are the main component and responsible for the rising phase of action potentials in excitable cells such as neurons, myocytes, and some certain types of glia. The dynamics of sodium channels can be classified into three different states: resting, active and inactive states.