Catecholamines are a group of biogenic amines primarily synthesized in the adrenal medulla or the cells of the sympathetic nervous system from the amino acid tyrosine through the intermediate product dopamine. Dopamine, adrenaline (epinephrine) and noradrenaline (norepinephrine) are members of this group. In response to the physical and emotional stress, catecholamines are released into the bloodstream and act as important hormones and neurotransmitters.

Catecholamines are a group of biogenic amines primarily synthesized in the adrenal medulla or the cells of the sympathetic nervous system from the amino acid tyrosine through the intermediate product dopamine. Dopamine, adrenaline (epinephrine) and noradrenaline (norepinephrine) are members of this group. In response to the physical and emotional stress, catecholamines are released into the bloodstream and act as important hormones and neurotransmitters.

Organic acids are defined as organic compounds with acidic properties. Because these acids are organic, their structure must contain a carbon atom. Carboxylic acid, with the molecular formula as RCOOH, is one of the most common organic acids. Sulfonic acid and alcohol are also organic acids.

Absolute Quantification is a targeted quantitative proteomics technique that exhibits robust efficacy and is being increasingly utilized for a wide variety of quantitative proteomics studies. AQUA strategy is for the absolute quantification (AQUA) of proteins and their modification states.

Acetylation is an important modification of proteins in cell biology. N-acetylation, or the transfer of an acetyl group to nitrogen, occurs in almost all eukaryotic proteins through both irreversible and reversible mechanisms.

Creative Proteomics provides N-terminal sequence analysis by both Edman and Mass spectrometry of therapeutic proteins, monoclonal antibodies and protein vaccines.

With the advancement in mass spectrometry technology, protein and peptide identification is no more tedious and time consuming. To help shorten the time duration of protein identification and enhance the accuracy of protein sequencing, Creative Proteomics has been long focused on optimizing our mass spectrometry technology platform. We have developed a comprehensive protein identification pipeline, which starts from sample preparation, protein separation and purification, followed by mass analysis, and finally to systematic bioinformatics analysis.

The evaluation of the spot patterns is the most demanding part of the 2-D electrophoresis technique, and the images would be analyzed comparatively and automatically.

The Western Blot is a widely used analytical technique for the detection of specific proteins in a sample of tissue homogenate or extract. It uses gel electrophoresis to separate native proteins by 3-D structure, or denatured proteins by the length of the polypeptide.

Creative Proteomics offers an integrated solution to the identification of low abundance proteins in complex biological sample through 2D electrophoresis. This technique sorts proteins according to two independent properties in two discrete steps. Each spot on the resulting two-dimensional array corresponds to a single protein species in the sample. Thus thousands of different proteins can be separated, and the information is obtained including the protein pI, the apparent molecular weight, and the amount of each protein.